What is With Dr.?
The WithDr.AC Night Serum series is a doctor's cosmetic developed by four doctors (running 14 clinics) who specialize in dermatology and cosmetic medicine. This serum focuses on the effects of vitamin A and its related compounds (retinoids) and vitamin C. After the initial redness (retinoid reaction) occurs when using the retinoid, it promotes cell turnover, awakening firmer, more translucent skin.
However, due to retinoid reactions, it was difficult to handle, and high-concentration products could only be used in hospitals. Therefore, doctors took the lead in creating high-concentration products that were easy to use for home care.
With Dr.AC Night Serum Series.
 
Recommended for:
・Those who are concerned about dullness or darkening*.
・Those who want clearer skin.
・I want to tighten my sagging skin.
・Those who suffer from oily skin or sebum problems.
- People who are not satisfied with the retinoid-containing cosmetics they are currently using.
*Due to dirt and old keratin
 
Effective against dullness and dark spots
Retinoids improve dull skin by accelerating the turnover of old keratin containing melanin, which is the cause of blemishes. They also thin the epidermis, leading to clearer skin. By using them in combination with hydroquinone, which suppresses the production of melanin, you can expect even better results.
 
Effective against pore and sebum problems
Retinoids suppress the secretion of sebaceous glands and open pores through the action of vitamin A. They act on dullness and dark spots caused by dirt and dead skin cells, and regulate sebum problems.
 
Gives skin firmness and radiance
It increases the amount of hyaluronic acid in the epidermis, giving the skin firmness and reducing the appearance of fine lines caused by dryness. Niacinamide and ceramide also work on fine lines caused by dryness.
 
We analyzed other cosmetics containing retinoids and developed our own unique formula.
Four practicing doctors have reformulated the formula to suit Japanese skin. The formula minimizes skin damage, resulting in little downtime and high effectiveness. What is retinoid? Retinoid, the beauty ingredient that is currently attracting the most attention, is a type of vitamin A that also exists in our bodies. It refers to vitamin A derivatives and synthetic compounds that are similar to vitamin A in terms of function and chemical structure. Retinoids are also found in foods (liver, green and yellow vegetables, eel, eggs, etc.), but it is thought that applying them directly to the skin is more effective. It is an essential ingredient for beautiful skin, bringing fresh firmness and luster to the skin.
 
summary
Cosmetics containing retinoids (vitamin A) are very popular and in demand at clinics, but they are quite complicated to use, have many side effects, and can only be purchased at hospitals. Also, many other cosmetics containing retinoids are developed and manufactured in the United States or South Africa, and cannot be said to be suitable for Japanese skin. The With Dr. series was created by a doctor who knows Japanese skin inside and out, aiming to maximize the effects of retinoids, reduce side effects, and make them easier to use.

How to use
Use 3 pumps of With Dr. once a day at night after washing your face and moisturizing. If you have sensitive skin, you can use 1 pump once a day. If you have a weak reaction, use 3 pumps of With Dr. before moisturizing.
 
If your skin is not used to retinoids, you may experience severe side effects (retinoid reactions). Therefore, it is necessary to start with level 1 and allow your skin to get used to it. It is said that the skin's turnover period is 28 days, but in reality it is often longer, usually around 38 to 46 days. By using level 1 for 1.5 months (45 days), you can allow your skin to get used to retinoids, and then proceed to level 2, which will allow you to use it comfortably.

*To be on the safe side, please avoid using this product during pregnancy. (Retinoids are also found in foods, so there is no need to worry too much if you use them without realizing you are pregnant.) You can use this product without any problems while breastfeeding.
With Dr.'s Commitment
Retinol for offense and defense
With Dr. aims to reduce the side effects of retinoids and maximize their effectiveness. The retinoids contain three types of aggressive pure retinol and defensive retinol: retinol linoleate, retinol palmitate, and tocopheryl retinoate. Other ingredients such as niacinamide, vitamin C derivatives, and vitamin E protect the skin from damage and keep it healthy.
 
A prescription that minimizes side effects
We pay particular attention to the pH of the formulation, making it a weak acid that is gentle on the skin. By incorporating a high concentration of panthenol, it is designed to reduce side effects. Compared to retinoid cosmetics made overseas, it contains as little surfactant as possible.
 
Effective skin care for Japanese skin
It is available in three levels, Level 1, Level 2, and Level 3 (sold only at medical institutions), so that you can use it comfortably. By gradually increasing the level, you can perform skin care safely and effectively. The concentration of aggressive retinol and vitamin C derivatives increases with each level. The results of clinical trials conducted on 300 Japanese people were analyzed and the concentration was adjusted to be effective and less likely to cause side effects.
 
Level 1: Allows the skin to become accustomed to the retinoid and penetrates it into the skin with protective vitamins.
Level 2: The formula contains the same amount of defensive retinoids, but with a higher concentration of aggressive retinoids, enhancing the effectiveness of the retinoids. The concentration of vitamin C derivatives is also higher.
Level 3: This product contains an even higher concentration of aggressive retinoids, the highest concentration available in Japan. This product is sold exclusively at clinics.
 
Side effects of retinoids When you first start using them, you may experience side effects such as stinging, dryness, and redness that may last for a few days to a few weeks (vitamin A reactions). These are not allergic reactions, and are not reactions to toxicity. They are natural reactions. Once the vitamin A reactions have subsided, you can expect your skin to improve.
 
*Note: Please avoid using this product during pregnancy as a precaution. (Retinoids are also found in foods, so there is no need to worry too much if you use them without realizing you are pregnant.) You can use this product without any problems while breastfeeding.
 
With Dr. Ingredients
High in antioxidant vitamins

4 types of retinoids
・Retinol linoleate
・Retinol palmitate,
・Retinoic acid tocopherol
Retinol
 
Vitamin C derivatives
Ascorbyl Hexyldecanoate

Vitamin B
Panthenol Niacinamide
 
Vitamin E
Tocopherols
 
Safe and secure Made in Japan
All Japanese products are made under strict control at our production factory in Fukui Prefecture.
 
Customer testimonials
 
UserVoice:01
It's moist and hydrating♪ Because it's a milky serum, it's moisturizing without being sticky, and it's good♪
 
UserVoice:02
It's easy to use and doesn't sting. It seems to be the mildest product, so there are no side effects such as peeling or stinging. Other companies' retinol cosmetics tend to sting and are difficult to use, but this one doesn't sting at all! I think it's good for people who don't want their skin to peel due to their job but still want to use retinol!
 
UserVoice:03
The packaging is cute♪ The packaging and containers are simple and cute, and I think they would fit in with any interior decor.
 
Q&A
 
When is it best to use it?
Use 3 pumps at night after washing your face and moisturizing. Spread it on your hands and gently apply it to your entire face. If you have sensitive skin, it may be easier to use it on your T-zone first.
 
How long does it take for a retinoid reaction to begin?
It usually starts in a few days and ends in a few weeks. In between, make sure to moisturize thoroughly and then use With. Dr. You can also reduce to one pump.
 
I don't have any reaction to retinoids...
It is designed to minimize irritating ingredients, contain plenty of ingredients with anti-inflammatory properties, and reduce retinoid reactions as much as possible. Therefore, in many cases, retinoid reactions do not occur very often, but this is not a problem. Please continue using it as is and proceed to Level 2.
 
I have atopic dermatitis. Can I use this product?
If your atopic dermatitis rash has healed, you can still use it. Please use it carefully, one pump at a time.
 
I have acne, can I use it?
Yes you can. Use it to prevent acne.
 
Can I use this with acne medication?
There is no problem. Use with caution when using Adapone as it may be too irritating to the skin.
 
Can I use it on my body?
There is no problem.
 
Can men use it too?
Of course you can use it.
 
When is it best to switch between levels 1, 2, and 3?
We recommend you level up every three months.
 
Can I use this product while pregnant or breastfeeding?
Please refrain from using this product during pregnancy. It can be used without problems while breastfeeding.
 
Can it be used in combination with hydroquinone?
Yes, the combination of retinoid and hydroquinone is called the University of Tokyo method, and is said to be particularly effective in treating dullness and dark spots.
 
Can I start straight from level 2?
If you are already using cosmetics containing retinoids, then this should be fine, but if not, then it's level 1.
I recommend starting with.
 
 
Vitamin A cosmetics for Japanese people.
There are three settings, from level 1, which is gentle, to level 3, which provides a definite effect on the skin. You can choose the level that suits your skin type.
 
Level 1 is a gentle vitamin A cream that can be used daily even by those new to vitamin A cosmetics. Level 2 is a vitamin A cream designed with an exquisite vitamin A concentration that suppresses reactions while still providing a steady feeling of effect. Level 3 is a high-concentration formula that can only be purchased at medical institutions. It brings an aggressive feeling to the skin.
 
Contains pure retinol that actively works on the skin, retinol linoleate that brings transparency, retinol palmitate that protects the skin, and tocopheryl retinoate that brings moisture to the skin. Four types of vitamin A with different functions work synergistically. In addition, it contains vitamin C derivatives such as "VCIP", an oil-soluble vitamin C that is easily absorbed into the skin and works for a long time, and "VC ethyl", which brightens the skin, to address dullness of the skin. In addition, to minimize negative reactions caused by vitamin A, it contains multiple anti-inflammatory ingredients as well as repair ingredients such as ceramide and panthenol that enhance the skin's barrier function. This vitamin A cream combines the powerful approach of vitamin A with the gentleness of protecting the skin.
 
How to use
 
After washing your face in the morning and evening and applying lotion, take an appropriate amount into your hand (approximately 1 to 3 pumps depending on your skin condition) and apply evenly to your entire face.
 
Precautions for use
 
*Please use with caution to ensure that no abnormalities occur on your skin.
If the cosmetics do not suit your skin, that is, in the following cases, discontinue use. Continuing to use the cosmetics may worsen the symptoms, so we recommend consulting a dermatologist. (1) If you experience any abnormalities such as redness, swelling, itchiness, irritation, loss of color (white spots, etc.) or darkening during use. (2) If the above-mentioned abnormalities appear on the skin on which the product was used and exposed to direct sunlight.
*You may experience dry skin or a tingling sensation while using this product.
*Please use sunscreen when going out during the day.
*Do not use on areas with abnormalities such as wounds, swellings, or eczema.
*Be careful not to get it in your eyes. If it does get in your eyes, rinse immediately with water without rubbing.
 
Component
Water, isotridecyl isononanoate, BG, caprylic/capric triglyceride, squalane, panthenol, cyclodextrin, cetanol, tocopherol, ascorbyl tetraisopalmitate, 3-O-ethyl ascorbic acid, phytosteryl/octyldodecyl lauroyl glutamate, ceramide NG, ceramide NP, ceramide AP, phytosphingosine, retinyl linoleate, retinyl palmitate, tocopheryl retinoate, retinol , bisabolol, stearyl glycyrrhetinate, allantoin, thioctic acid, rosemary leaf extract, niacinamide, polysorbate 60, apricot kernel oil, shea butter, mineral oil, stearyl alcohol, corn oil, polysorbate 20, dimethicone, polyacrylate crosspolymer-6, behenyl alcohol, polyglyceryl-10 pentastearate, sodium stearoyl lactylate, t-butanol, potassium hydroxide, 1,2-hexanediol, phenoxyethanol